Speak to your doctor if you have muscle pain, tenderness or weakness that cannot be explained – for example, pain that is not caused by physical work. How statins cause muscle pain is not fully understood. Co-Q10 helps some people. So, if your pain is localized to only one area of your body, then it’s probably related to something else. Myalgia: Muscle pain which is experienced by 2% to 10% of people taking statins. Statin-related muscle problems are more likely to occur in people who exercise vigorously, especially if they begin to do so at a rapid rate rather than slowly building up intensity. It is also more common in people taking a variety of other medications, including Lopid (gemfibrozil), as well as steroids, cyclosporine, or niacin. Drug-Dependent: The risk of statin-associated myopathy has been shown to increase as a patient’s statin dose increases. Another theory is that statin… In a Cochrane Foundation Analysis of 37,939 individuals involved in nine clinical trials, 9.4% of those receiving statins experienced myalgia, a rate I would like to know if anyone is taking something that comes with less side effects. So, if your pain is localized to only one area of your body, then it’s probably related to something else. 7 Several statins are metabolized through the CYP450 system (TABLE 1). MONDAY, June 3 (HealthDay News) -- People taking statin drugs to lower their cholesterol may slightly increase their risk for muscle and joint diseases … My husband is having a problem with extreme fatigue, muscle pain, and severe tinnitus since starting a statin, rosuvastatin, a couple of weeks ago. 6,9,20-26 Therefore, drugs that). Statins can occasionally cause muscle inflammation (swelling) and damage. Other statins might not cause the muscle aches -- pravastatin and fluvastatin are least likely to have these side effects, and I would recommend those if a person really needed to be on a statin. In general, muscle symptoms directly due to a statin drug cause diffuse muscle aches. Which statin has the least side effects? One theory is that statins may affect a protein in muscle cells, which decreases muscle growth.

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